UNC CENTER FOR FUNCTIONAL GI & MOTILITY DISORDERS


Do you suffer from IBS and want to know why?

The UNC Center for Functional GI and Motility Disorders is recruiting volunteer subjects with IBS, to participate in a health research study that is looking at a broad range of genetic and environmental factors that may cause or influence Irritable Bowel Syndrome.
Participation requires either a single overnight visit (for out of state subjects) or two outpatient vists, at the UNC Medical Center in Chapel Hill, during which you will complete:

  • A 3.5 hour hydrogen breath test for bacterial overgrowth and lactose (milk) intolerance. You will also complete psychological and medical history questionnaires at the same time.
  • A water drinking test (up to 1 liter of water) to evaluate how much fluid your stomach can contain before you experience discomfort or pain
  • A listening task where you listen to several series of words and are asked to repeat the ones you remember after each series
  • A test of the sensitivity of your bowel by placing a small plastic tube (width of a pencil) with a balloon on it into your rectum, a basic blood count (CBC) and C-reactive protein test (which is a marker for inflammation).
  • Taking a blood sample for basic blood count (CBC) and C-reactive protein test (which is a marker for inflammation)
  • Taking another blood sample for genetic testing

Upon completion of the study you will receive $250 for your time and participation. You may also earn an additional bonus of up to $56 depending on how well you do on the listening task

In order to determine if you are eligible for the study, you will need to answer a few questions. If you have been diagnosed with IBS by a doctor, please click here to proceed:


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Are you a healthy individual willing to participate in the study?

We also need healthy participants with no gastrointestinal symptoms to participate. The steps include:

  • One 4-5 hour visit to UNC
  • Filling out psychological and health questionnaires
  • A hydrogen breath test for bacterial overgrowth and lactose (milk) intolerance
  • A water drinking test (up to 1 liter of water) to evaluate how much fluid your stomach can contain before you experience discomfort or pain
  • A listening task where you listen to several series of words and are asked to repeat the ones you remember after each series
  • Taking a blood sample for basic blood count (CBC) and a C-reactive protein test (which is a marker for inflammation)
  • Taking another blood sample for genetic testing

Upon completion of the study you will receive $100 for your time and participation. You may also earn an additional bonus of up to $56 depending on how well you do on the listening task

In order to determine if you are eligible for the study, you will need to answer a few questions. If you are healthy and do not have any gastrointestinal symptoms, please click here to proceed:



Research nurse: Lenore Keck, e-mail akeck@med.unc.edu